Knowledge of the risk for hereditary cancer provides physicians with several different options for the management of a patient:
- International management guidelines are available for a number of syndromes associated with hereditary cancer predisposition.
- Dramatic reduction in the occurrence of primary tumors can be achieved:
- Prophylactic surgery is recommended in healthy individuals found to carry a pathogenic mutation in a number of the genes included in the panel.
- This type of surgery can reduce the risk of developing cancer by more than 90%
- International guidelines recognize the value of the use of hereditary gene panels:
- Cost effective
- More efficient
- More informative
- Novel targeted therapy drugs have been and are being developed. They are designed to target the specific mutated protein, individualizing the treatment of the patients.