Knowledge of the risk for hereditary cancer provides physicians with several different options for the management of a patient:

  • International management guidelines are available for a number of syndromes associated with hereditary cancer predisposition.
  • Dramatic reduction in the occurrence of primary tumors can be achieved:
    • Prophylactic surgery is recommended in healthy individuals found to carry a pathogenic mutation in a number of the genes included in the panel.
    • This type of surgery can reduce the risk of developing cancer by more than 90%
  • International guidelines recognize the value of the use of hereditary gene panels:
    • Cost effective
    • More efficient
    • More informative
  • Novel targeted therapy drugs have been and are being developed. They are designed to target the specific mutated protein, individualizing the treatment of the patients.

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